Blar i Bergen Open Research Archive på forfatter "Grindheim, Sindre"

Viser treff 1-2 av 2

    • Humanized Ovarian Cancer Patient-Derived Xenografts for Improved Preclinical Evaluation of Immunotherapies 

      Kleinmanns, Katrin; Gullaksen, Stein-Erik; Bredholt, Geir; Davidson, Ben; Torkildsen, Cecilie Fredvik; Grindheim, Sindre; Bjørge, Line; Cormack, Emmet Mc (Journal article; Peer reviewed, 2022)
      High-grade serous ovarian cancer (HGSOC) has poor prognosis and new treatment modalities are needed. Immunotherapy, with checkpoint inhibitors, have demonstrated limited impact. To evaluate the suitability for immunotherapeutics, ...

    • Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study 

      Grindheim, Sindre; Ebbing, Cathrine; Karlsen, Henriette Odland; Skulstad, Svein Magne; Real, Francisco Gomez; Lønnebotn, Marianne; Løvvik, Tone Shetelig; Vanky, Eszter; Kessler, Jørg (Journal article; Peer reviewed, 2022-01-28)
      Background: Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ...